Investigación y ensayos clínicos

Avanzar en oncología quirúrgica

Trasladar la investigación a mejores resultados en enfermedades peritoneales y sarcomas — enfermedades raras que exigen evidencia propia.

Áreas de investigación activas

Líneas de trabajo

Carcinomatosis Peritoneal

  • Factores pronósticos en CRS+HIPEC de origen colorrectal
  • Nuevos regímenes de fármacos HIPEC
  • Calidad de vida tras cirugía citorreductora
  • Selección de pacientes y optimización del PCI

Sarcoma Retroperitoneal

  • Resultados de la resección compartimental
  • Estrategias neoadyuvantes
  • Patrones de recidiva y manejo
  • Registros colaborativos internacionales
  • Primer autor del primer consenso ERAS para cirugía del sarcoma retroperitoneal primario (consenso hispano-luso)

Pseudomixoma Peritoneal

  • Clasificación y pronóstico del pseudomixoma apendicular
  • Seguimiento a largo plazo tras citorreducción completa
  • Papel del HIPEC en enfermedad de bajo y alto grado

Nefroprotección durante HIPEC

  • Prevención de la nefrotoxicidad por cisplatino-HIPEC
  • Estudio comparativo cilastatina vs. tiosulfato
  • Monitorización de biomarcadores de protección renal

Ensayos clínicos

Estudios en curso

Reclutando

Cilastatina vs. tiosulfato: nefroprotección en CRS+HIPEC con cisplatino

Estudio prospectivo que evalúa la nefroprotección con cilastatina frente a tiosulfato sódico en pacientes sometidos a CRS+HIPEC con cisplatino.

Colaboración internacional

Una red global en oncología peritoneal

La carcinomatosis peritoneal es infrecuente en cada centro por separado. Ningún hospital reúne por sí solo los casos necesarios para responder a las preguntas que importan, y por eso este trabajo se hace en red.

Pekín · julio 2026

International Research Center for Peritoneal Surface Oncology

School of Clinical Medicine, Tsinghua University

Participación en el programa de intercambio académico que ha dado origen al IRCPSO, con equipos de China, Japón, Países Bajos, España e India en torno a un objetivo común: mejorar el tratamiento de la carcinomatosis peritoneal.

Citorreducciones retransmitidas en directo, proyectos multicéntricos y un registro mundial propuesto para el mesotelioma peritoneal maligno difuso.

Intercambio continuado

Beijing Tsinghua Changgung Hospital

Tsinghua University · Pekín, China

Intercambio académico y quirúrgico con el equipo del BTCH y en Harbin: sesiones operatorias conjuntas y puesta en común de técnicas de tratamiento de la enfermedad maligna peritoneal.

El vínculo con Tsinghua es la base sobre la que se ha construido la participación en el IRCPSO.

Publicaciones

Trabajo revisado por pares

50 publicaciones

  1. 2026·Cirugía EspañolaSarcoma

    ¿Estamos tratando bien el tumor desmoide en España? Resultados de la primera encuesta nacional

  2. 2026·Annals of Surgical OncologySarcoma

    ASO Author Reflections: Enhanced Recovery in Retroperitoneal Sarcoma Surgery — From Concept to Consensus

  3. 2026·Annals of Surgical OncologyPeritoneal

    ASO Visual Abstract: Protective Effect of Diuresis During Hyperthermia on Acute Kidney Injury in Cytoreductive Surgery with HIPEC

  4. 2026·Annals of Surgical OncologySarcoma

    Consensus Guidelines on Perioperative Care in Primary Retroperitoneal Sarcoma Surgery

  5. 2026·Cirugía EspañolaSarcoma

    Cuidados perioperatorios en la cirugía del sarcoma retroperitoneal primario: una encuesta hispano-lusa sobre prácticas actuales

  6. 2026·CancersSarcoma

    Experience of a Referral Center with Desmoid Tumors, Part 2: A Retrospective Analysis of 109 Cases

  7. 2026·Clinical and Translational OncologyPeritoneal

    Pressurised intraperitoneal aerosol chemotherapy (PIPAC) for peritoneal metastases: a scoping review of clinical evidence across emerging indications

  8. 2026·Annals of Surgical OncologyPeritoneal

    Protective Effect of Diuresis During Hyperthermia on Acute Kidney Injury in Cytoreductive Surgery with HIPEC

  9. 2026·CancersSarcoma

    Surgical Management and Therapeutic Strategy of Uterine Sarcoma According to Histological Subtype and Staging: Updated Review and Recommendations

  10. 2025·CancersSarcoma

    Desmoid Tumors — Experience from a Referral Center, Part 1: Multidisciplinary Review and Practical Recommendations

  11. 2025·CancersSarcoma

    Diagnostic Delay in Soft Tissue Sarcomas: A Review

  12. 2025·CancersSarcoma

    Ibero-American Consensus for the Management of Liver Metastases of Soft Tissue Sarcoma: Updated Review and Clinical Recommendations

  13. 2023·CancersPeritoneal

    Appendiceal Mucinous Neoplasms: From Clinic to Pathology and Prognosis

  14. 2023·European Journal of Surgical OncologyPeritoneal

    External multicentre validation of pseudomyxoma peritonei PSOGI-Ki67 classification

  15. 2023·CancersSarcoma

    Updated Review and Clinical Recommendations for the Diagnosis and Treatment of Patients with Retroperitoneal Sarcoma by the Spanish Sarcoma Research Group (GEIS)

  16. 2022·Annals of Surgical OncologyPeritoneal

    ASO Author Reflections: Predicting Prognosis in Patients with Pseudomyxoma

  17. 2022·Cirugía y CirujanosOtros

    Mecanismos del precondicionamiento regenerativo en hepatectomías subtotales en modelo porcino

  18. 2022·Annals of Hepato-Biliary-Pancreatic SurgeryOtros

    Neoadjuvant therapy impact in early pancreatic cancer: bioborderline vs. non-bioborderline

  19. 2022·Annals of Surgical OncologyPeritoneal

    Validation of a Nomogram to Predict Recurrence in Patients with Mucinous Neoplasms of the Appendix with Peritoneal Dissemination After CRS and HIPEC

  20. 2021·Annals of Hepato-Biliary-Pancreatic SurgeryOtros

    Advances in neoadjuvant therapy for resectable pancreatic cancer over the past two decades

  21. 2021·British Journal of SurgeryOtros

    Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic

  22. 2021·BJS OpenPeritoneal

    Defining stage in mucinous tumours of the appendix with peritoneal dissemination: the importance of grading terminology: systematic review

  23. 2021·Annals of Case ReportsSarcoma

    Dermatofibrosarcoma Protuberans (DFSP) with Fibrosarcomatous Transformation: A Case Report

  24. 2021·International Journal of Molecular SciencesPeritoneal

    Effect of Cilastatin on Cisplatin-Induced Nephrotoxicity in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy

  25. 2021·The Lancet OncologyOtros

    Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study

  26. 2021·British Journal of SurgeryOtros

    SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

  27. 2021·AnaesthesiaOtros

    Timing of surgery following SARS‐CoV‐2 infection: an international prospective cohort study

  28. 2021·Journal of Clinical PathologyPeritoneal

    Which classification system defines best prognosis of mucinous neoplasms of the appendix with peritoneal dissemination: TNM vs PSOGI?

  29. 2020·American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant SurgeonsOtros

    Bariatric surgery and transplantation: A bridge not so far.

  30. 2020·The British journal of surgeryOtros

    Delaying surgery for patients with a previous SARS-CoV-2 infection.

  31. 2020·Journal of clinical oncology : official journal of the American Society of Clinical OncologyOtros

    Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

  32. 2020·The British journal of surgeryOtros

    Elective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans.

  33. 2020·Transplantation ProceedingsOtros

    Evaluation of Plasma Disappearance Rate Indocyanine Green Clearance as a Predictor of Liver Graft Rejection in Donor Brain Death

  34. 2020·The British journal of surgeryOtros

    Global guidance for surgical care during the COVID-19 pandemic.

  35. 2020·CancerOtros

    Head and neck cancer surgery during the COVID-19 pandemic: An international, multicenter, observational cohort study.

  36. 2020·The British journal of surgeryOtros

    Impact of asymptomatic COVID-19 patients in global surgical practice during the COVID-19 pandemic.

  37. 2020·Lancet (London, England)Otros

    Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study.

  38. 2020·Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and IrelandOtros

    Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic.

  39. 2020·Journal of Global HealthOtros

    Screening policies, preventive measures and in-hospital infection of COVID-19 in global surgical practices

  40. 2020·British Journal of SurgeryOtros

    Surgeons' fear of getting infected by COVID19: A global survey

  41. 2019·Journal of Gastrointestinal SurgeryOtros

    Comprehensive Characterization of a Porcine Model of The “Small-for-Flow” Syndrome

  42. 2019·Transplantation ProceedingsOtros

    Donor Risk Index Has an Impact in Intraoperative Measure of Hepatic Artery Flow and in Clearance of Indocyanine Green: An Observational Cohort Study

  43. 2019·World journal of hepatologyOtros

    Hepatic flow is an intraoperative predictor of early allograft dysfunction in whole-graft deceased donor liver transplantation: An observational cohort study.

  44. 2019·Archives of Organ TransplantationOtros

    Purpose of the measurement of intraoperative hepatic hemodynamics in liver transplant surgery

  45. 2019·Surgery: Current Trends and InnovationsSarcoma

    Radiation-Induced Intrapelvic Osteosarcoma Treated with Radical Pelvic Surgery: Case Report and Literature Review

  46. 2018·Current Transplantation ReportsOtros

    DCD Liver Transplant: a Meta-review of the Evidence and Current Optimization Strategies

  47. 2018·The Spine JournalSarcoma

    Role of intraoperative radiotherapy in the treatment of sacral chordoma

  48. 2017·SurgeryOtros

    Preconditioning by portal vein embolization modulates hepatic hemodynamics and improves liver function in pigs with extended hepatectomy

  49. 2016·Cirugía EspañolaOtros

    Linfoma adrenal primario; una entidad poco frecuente en el diagnóstico diferencial de las tumoraciones suprarrenales

  50. 2013·Journal of Liver: Disease & TransplantationOtros

    Early Changes in Small-for-Flow Syndrome: An Experimental Model

Ver la lista completa en ORCID ↗

¿Interesado en colaborar?

Abierto a colaboraciones de investigación en oncología peritoneal y sarcoma.